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注意缺陷多动障碍患儿嗅觉功能改变以及与症状的关系

The change of olfactory function in children with attention deficit hyperactivity disorder and its relationship with symptoms

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【作者】 涂献珠平晶陈亮金森坚许超豪刘美如

【Author】 TU Xian-zhu;PING Jing;CHEN Liang;JIN Sen-jian;XU Chao-hao;LIU Mei-ru;the Seventh People’s Hospital of Wenzhou;

【通讯作者】 涂献珠;

【机构】 温州市第七人民医院

【摘要】 目的:分析注意缺陷多动障碍(ADHD)患儿嗅觉功能改变以及与症状的关系。方法:选取2018年6月至2020年3月在温州市第七人民医院住院及门诊的100例ADHD患儿纳入研究组,并将100名健康儿童纳入对照组,采用嗅棒分别检测两组嗅觉敏感性和气味鉴别能力,比较两组间嗅觉功能差异;同时采用SNAP-IV量表评估ADHD症状,利用多元线性回归方法分析嗅觉功能水平与其症状严重程度之间的关系。结果:研究组嗅觉敏感性评分(t=10.46,P<0.001)和气味鉴别能力评分(t=12.35,P<0.001)显著差于对照组;ADHD症状评分与嗅觉敏感性评分、气味鉴别力评分存在显著的负向线性回归关系(F=107.88,P<0.001)。结论:ADHD患儿存在明显的嗅觉功能降低,同时患儿嗅觉功能水平与其症状水平之间存在负相关。

【Abstract】 Objective:To analyze the change of olfactory function and its relationship with symptoms in children with attention deficit hyperactivity disorder(ADHD). Method:100 children with ADHD who were hospitalized and outpatients of Wenzhou Seventh People’s Hospital from June 2018 to March 2020 were selected into the study group, and 100 healthy children were included in the control group.The olfactory stick was used to detect the smell threshold and smell identification ability of the two groups respectively.The difference in olfactory function between the two groups was compared.At the same time, the SNAP-IV scale was used to assess the symptoms of ADHD,with multiple linear regression method to analyze the relationship between the level of olfactory function and the severity of symptoms. Results:The olfactory sensitivity score(t=10.46,P<0.001) and odor discrimination score(t=12.35,P<0.001) of the study group were significantly worse than those of the control group.There was a significant negative linear regression relationship between ADHD symptom score, olfactory threshold score and smell identification score(F=107.88,P<0.001). Conclusion: Children with ADHD have a significant decrease in the olfactory function which has negative correlation with the level of symptoms.

【基金】 温州市医疗卫生科技项目(Y20180494)
  • 【文献出处】 临床精神医学杂志 ,Journal of Clinical Psychiatry , 编辑部邮箱 ,2021年03期
  • 【分类号】R749.94
  • 【下载频次】65
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